The Essential Role of
Tears in Healthy Eyes

More than just moisture, tears and the tear film support overall ocular health in a variety of ways. Under or over tear production can lead to various diseases and conditions. Tears help to:

Lubricate the cornea, eyelids and conjunctiva (the tissue that lines the eyelids)

Protect the eyes against infection

Provide oxygen and nutrients to the cornea

Remove metabolic by-products like carbon dioxide

Play a role in the local immune defense

Wash away irritating particles or foreign bodies

Keep the eye surface smooth and clear

The Essential Role of Tears in Healthy Eyes

More than just moisture, tears and the tear film support overall ocular health in a variety of ways. Under or over tear production can lead to various diseases and conditions. Tears help to:

Lubricate the cornea, eyelids and conjunctiva (the tissue that lines the eyelids)

Protect the eyes against infection

Provide oxygen and nutrients to the cornea

Remove metabolic by-products like carbon dioxide

Play a role in the local immune defense

Wash away irritating particles or foreign bodies

Keep the eye surface smooth and clear

What is Dry Eye?

Dry Eye is a common eye condition in dogs that occurs when their tear glands are not able to produce the normal amount of tears. The condition can be very painful because without tears, the eyes feel dry and irritated (feeling like sandy grit in the eye) and are more prone to infections and ulcers. If left untreated, this can lead to pigmentation changes and scarring of the eye surface and eventually even blindness.

Signs of Dry Eye

The appearance of Dry Eye can be varied and subtle, especially in the early stages. If your dog has any of the following signs, you should make an appointment with your veterinarian.

Blinking

Blinking or rubbing eyes excessively.
Trying to keep eyes closed

Redness

Bloodshot appearance
and inflammation

Discharge

Discharge from
the eyes

Dull appearance

Dull or
dry appearance

Conjunctivitis

Frequent conjunctivitis, eye infections
or corneal ulcers

Dark pigment

Dark pigment on the surface
of the eyes

Please note: the eyes of some dogs affected by Dry Eye look quite normal, despite severely reduced tear production and destruction of the tear glands. Being aware of the signs is a big step in getting it diagnosed early before too much tear tissue is destroyed and adverse changes to the eye develop. Veterinary specialists in ophthalmology recommend testing virtually all sore eyes for Dry Eye to make sure it’s caught early.

Dry eye affects up to 20% of predisposed breeds2

2 Williams D, Mann B. A Crosslinked HA-Based Hydrogel Ameliorates Dry Eye Symptoms in Dogs. International Journal of Biomaterials. Volume 2013, Article ID 460437

Predisposed Breeds

All breeds of dogs can develop Dry Eye at any age, but some are much more prone to the condition. Dog breeds particularly susceptible to Dry Eye include:

English Cocker spaniel

West Highland White terrier

Cavalier King Charles spaniel

Shih Tzu

Yorkshire terrier

Bulldog

Pekingese

Pug

Lhasa Apso

Veterinary specialists in ophthalmology recommend testing susceptible breeds regularly and many owners elect to proactively have their dog tested during routine appointments.

Diagnosing Dry Eye

Your veterinarian will perform a quick and painless test on your dog’s eyes called the Schirmer Tear Test. It involves placing a special strip of paper into the eye and holding it in place for 60 seconds to provide a measure of the amount of tears your dog produces in one minute. The test is typically done in both eyes because the findings can be quite different. Your veterinarian will assess these results, along with any other signs your dog is exhibiting, to determine if your dog has Dry Eye.

If your dog is not producing enough tears, treatment should be started immediately. The earlier the condition is diagnosed the more likely that treatment will be successful. If your dog has any of the signs listed above or is a breed at higher risk, talk to your veterinarian about testing or other ideas to help your dog.

Dry Eye Treatment

In most cases, Dry Eye requires treatment for life since there is no permanent cure for the destruction of tear glands. Once diagnosis has been made, the regimen is typically two‑fold:

SentrX-Icon-DryEyeTreatment-Prescription

1. PRESCRIPTION OINTMENT with cyclosporine: To treat the underlying condition, the veterinarian prescribes an eye ointment that protects the tear glands from being attacked by the immune system.

By the time Dry Eye is typically diagnosed, the gland destruction is so advanced therapy may be less effective. This means tear replacement drops that hydrate and lubricate the eye surface are often required.

Even in dogs that respond well to treatment with cyclosporine prescriptions, additional tear supplementation is still recommended to keep the eyes as comfortable and pain-free as possible.

SentrX-Icon-DryEyeTreatment-DailyTearReplacement

2. DAILY TEAR REPLACEMENT: Considered an essential component in the management of Dry Eye to keep eyes lubricated, most veterinarians recommend lubricating drops that replace natural tears to keep the eyes moist and protected.

These are only supplemental and do not replace treatment with cyclosporine. However, the majority of cases will benefit from long-term use of tear replacement drops, in addition to cyclosporine, to keep the eyes as comfortable as possible.